RESEARCH

Research interests

알츠하이머 치매, 퇴행성뇌질환
근감소증, 비만, 대사질환
Extracellular Vesicle, Exosome, Biomarker

Research

Thesis펼치기
- Pharmacogenetic Studies on the Polymorphism of Flavin-containing Monooxygenase 3 (FMO3) of Human Liver, 2000
Journal Articles펼치기
- Ketogenic diet with aerobic exercise can induce fat browning: potential roles of β-hydroxybutyrate, FRONTIERS IN NUTRITION, 2024
- Mitochondrial Adaptations in Aging Skeletal Muscle: Implications for Resistance Exercise Training to Treat Sarcopenia, LIFE-BASEL, Vol.14,No.8, 2024
- Evaluation of ATNPD Framework and Biofluid Markers to Predict Cognitive Decline in Early Parkinson Disease, NEUROLOGY, 2024
- Effects of physical activity participation on cognitive impairment in older adults population with disabilities, FRONTIERS IN PUBLIC HEALTH, Vol.12, 2024
- 미토콘드리아 산소호흡 측정방법, Exercise Science, 2023
- Alzheimer Disease Biomarkers: Moving from CSF to Plasma for Reliable Detection of Amyloid and tau Pathology, CLINICAL CHEMISTRY, Vol.69,No.11, 1247~1259, 2023
- Repositioning of Anti-Diabetic Drugs against Dementia: Insight from Molecular Perspectives to Clinical Trials, INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, Vol.24,No.14, 2023
- Heme-binding protein 1 delivered via pericyte-derived extracellular vesicles improves neurovascular regeneration in a mouse model of cavernous nerve injury, INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES, 2023
- Melatonin and Exercise Counteract Sarcopenic Obesity through Preservation of Satellite Cell Function, INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, Vol.24,No.7, 2023
- Argonaute 2 Restores Erectile Function by Enhancing Angiogenesis and Reducing Reactive Oxygen Species Production in Streptozotocin (STZ)-Induced Type-1 Diabetic Mice, INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023
- Contribution of High-Intensity Interval Exercise in the Fasted State to Fat Browning: Potential Roles of Lactate and β-Hydroxybutyrate, MEDICINE & SCIENCE IN SPORTS & EXERCISE, Vol.55,No.7, 1160~1171, 2023
- Dynapenic-abdominal obesity as an independent risk factor for chronic kidney disease in postmenopausal women: a population-based cohort study, MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY, Vol.29,No.9, 1040~1046, 2022
- Circulating micro-RNAs differentially expressed in Korean Alzheimer's patients with brain Ab accumulation activate amyloidogenesis, JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES, 2022
- Development of Alzheimer’s Disease Biomarkers: From CSF- to Blood-Based Biomarkers, Biomedicines, 2022
- Pericyte-derived extracellular vesicles-mimetic nanovesicles improves peripheral nerve regeneration in mouse models of sciatic nerve transection, INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, Vol.49,No.2, 2022
- Serum neurofilament light chain level as a predictor of cognitive stage transition, ALZHEIMERS RESEARCH & THERAPY, Vol.14,No.1, 2022
- Exercise Training Attenuates Ovariectomy-Induced Alterations in Skeletal Muscle Remodeling, Apoptotic Signaling, and Atrophy Signaling in Rat Skeletal Muscle, INTERNATIONAL NEUROUROLOGY JOURNAL, Vol.25, 47~54, 2021
- Alzheimer's cerebrospinal biomarkers from Lumipulse fully automated immunoassay: concordance with amyloid-beta PET and manual immunoassay in Koreans CSF AD biomarkers measured by Lumipulse in Koreans, ALZHEIMERS RESEARCH & THERAPY, Vol.13,No.1, 2021
- Sirtuin 1-dependent regulation of high mobility box 1 in hypoxia-reoxygenated brain microvascular endothelial cells: roles in neuronal amyloidogenesis, CELL DEATH & DISEASE, Vol.11,No.12, 2020
- Exercise as a Therapeutic Strategy for Sarcopenia in Heart Failure: Insights into Underlying Mechanisms, CELLS, Vol.9,No.10, 2020
- Evolution of Alzheimer's Disease Cerebrospinal Fluid Biomarkers in Early Parkinson's Disease, ANNALS OF NEUROLOGY, Vol.88,No.3, 574~587, 2020
- Aging Promotes Mitochondria-Mediated Apoptosis in Rat Hearts, LIFE-BASEL, Vol.10,No.9, 2020
- 회복 처치 방법에 따른 주짓수 모방 시합 중과 후의 신체수행력 및염증반응, Exercise Science, Vol.29,No.3, 214~224, 2020
- Effects of Aerobic Exercise on Tau and Related Proteins in Rats with Photochemically-Induced Infarction, JOURNAL OF ALZHEIMERS DISEASE, Vol.76,No.4, 1391~1402, 2020
- Effects of Aerobic Exercise on Tau and Related Proteins in Rats with the Middle Cerebral Artery Occlusion, INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, Vol.21,No.16, 2020
- Exercise Training Protects against Atorvastatin-Induced Skeletal Muscle Dysfunction and Mitochondrial Dysfunction in the Skeletal Muscle of Rats, JOURNAL OF CLINICAL MEDICINE, Vol.9,No.7, 2020
- Experimental Models of Sarcopenia: Bridging Molecular Mechanism and Therapeutic Strategy, CELLS, Vol.9,No.6, 2020
- Re-Setting the Circadian Clock Using Exercise against Sarcopenia, INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, Vol.21,No.9, 2020
- Autophagy in Neurodegenerative Diseases: A Hunter for Aggregates, INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, Vol.21,No.9, 2020
- Telomere shortening reflecting physical aging is associated with cognitive decline and dementia conversion in mild cognitive impairment due to Alzheimer's disease, AGING-US, Vol.12,No.5, 4407~4423, 2020
- Effects of aging and exercise training on mitochondrial function and apoptosis in the rat heart, PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY, Vol.472,No.2, 179~193, 2020
- Balance and Mobility Performance Along the Alzheimer's Disease Spectrum, JOURNAL OF ALZHEIMERS DISEASE, Vol.73,No.2, 633~644, 2020
- Embryonic stem cell-derived extracellular vesicle-mimetic nanovesicles rescue erectile function by enhancing penile neurovascular regeneration in the streptozotocin-induced diabetic mouse, SCIENTIFIC REPORTS, Vol.9, 2019
- Enrichment of Exosome-Like Extracellular Vesicles from Plasma Suitable for Clinical Vesicular miRNA Biomarker Research, JOURNAL OF CLINICAL MEDICINE, Vol.8,No.11, 2019
- Association of Nutritional Status with Cognitive Stage in the Elderly Korean Population: The Korean Brain Aging Study for the Early Diagnosis and Prediction of Alzheimer's Disease, JOURNAL OF CLINICAL NEUROLOGY, Vol.15,No.3, 292~300, 2019
- New 20 m Progressive Shuttle Test Protocol and Equation for Predicting the Maximal Oxygen Uptake of Korean Adolescents Aged 13-18 Years, INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH, Vol.16,No.13, 2019
- AMPK Alters Detrusor Contractility During Emptying in Normal Bladder and Hypertrophied Bladder with Partial Bladder Outlet Obstruction via CaMKK, INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, Vol.20,No.11, 2019
- Effects of a single bout of exercise on mitochondria-mediated apoptotic signaling in rat cardiac and skeletal muscles, Journal of exercise rehabilitation, Vol.15,No.4, 512~517, 2019
- Extracellular Vesicle as a Source of Alzheimer's Biomarkers: Opportunities and Challenges, INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, Vol.20,No.7, 2019
- Inhibition of oxaliplatin-induced neurotoxicity by silymarin through increased expression of brain-derived neurotrophic factor and inhibition of p38-MAPK, Molecular & Cellular Toxicology, Vol.15,No.2, 145~152, 2019
- Clinical and Biomarker Characteristics According to Clinical Spectrum of Alzheimer's Disease (AD) in the Validation Cohort of Korean Brain Aging Study for the Early Diagnosis and Prediction of AD, JOURNAL OF CLINICAL MEDICINE, Vol.8,No.3, 2019
- Amyloid beta in nasal secretions may be a potential biomarker of Alzheimer's disease, SCIENTIFIC REPORTS, Vol.9, 2019
- 남녀 청소년의 심폐지구력 평가를 위한 Step test 추정식의 일치도 평가, Exercise Science, Vol.28,No.1, 66~73, 2019
- Roles of myokines in exercise-induced improvement of neuropsychiatric function, PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY, Vol.471,No.3, 491~505, 2019
- Association of Circulating Irisin Concentrations with Weight Loss after Roux-en-Y Gastric Bypass Surgery, INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH, Vol.16,No.4, 2019
- Lactate overload inhibits myogenic activity in C2C12 myotubes, OPEN LIFE SCIENCES, Vol.14,No.1, 29~37, 2019
- Exercise Training Attenuates Obesity-Induced Skeletal Muscle Remodeling and Mitochondria-Mediated Apoptosis in the Skeletal Muscle, INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH, Vol.15,No.10, 2018
- Roles of Exosome-Like Vesicles Released from Inflammatory C2C12 Myotubes: Regulation of Myocyte Differentiation and Myokine Expression, CELLULAR PHYSIOLOGY AND BIOCHEMISTRY, Vol.48,No.5, 1829~1842, 2018
- Near-Normalized Gene Expression Profiles in Bladder With Detrusor Overactivity in Rats With Bladder Outlet Obstruction After Deobstruction, INTERNATIONAL NEUROUROLOGY JOURNAL, Vol.21,No.4, 247~258, 2017
- Effects of exercise on obesity-induced mitochondrial dysfunction in skeletal muscle, KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY, Vol.21,No.6, 567~577, 2017
- Effects of task-specific rehabilitation training on tau modification in rat with photothrombotic cortical ischemic damage, NEUROCHEMISTRY INTERNATIONAL, Vol.108, 309~317, 2017
- Extracellular Vesicles as a Source of Urological Biomarkers: Lessons Learned From Advances and Challenges in Clinical Applications to Major Diseases, INTERNATIONAL NEUROUROLOGY JOURNAL, Vol.21,No.2, 83~96, 2017
- Multiple modality biomarker prediction of cognitive impairment in prospectively followed de novo Parkinson disease, PLOS ONE, Vol.12,No.5, 2017
- Chronological changes in the expression of phosphorylated tau and 5-AMP-activated protein kinase in the brain of senescence-accelerated P8 mice, MOLECULAR MEDICINE REPORTS, Vol.15,No.5, 3301~3309, 2017
- Harnessing Cerebrospinal Fluid Biomarkers in Clinical Trials for Treating Alzheimer's and Parkinson's Diseases: Potential and Challenges, JOURNAL OF CLINICAL NEUROLOGY, Vol.12,No.4, 381~392, 2016
- Exosomes as the source of biomarkers of metabolic diseases, Annals of Pediatirc Endocrinology & Metabolism , Vol.21,No.3, 119~125, 2016
- Controls of Nuclear Factor-Kappa B Signaling Activity by 5 '-AMP-Activated Protein Kinase Activation With Examples in Human Bladder Cancer Cells, INTERNATIONAL NEUROUROLOGY JOURNAL, Vol.20,No.3, 182~187, 2016
- Effects of Lactic Acid on the Expression of Myokines in C2C12 Myotubes, Exercise Science, Vol.25,No.3, 174~182, 2016
- CSF biomarkers associated with disease heterogeneity in early Parkinson's disease: the Parkinson's Progression Markers Initiative study, ACTA NEUROPATHOLOGICA, Vol.131,No.6, 935~949, 2016
- Cerebrospinal fluid amyloid beta1-42, tau, and alpha-synuclein predict the heterogeneous progression of cognitive dysfunction in Parkinson's disease, JOURNAL OF MOVEMENT DISORDERS, Vol.9,No.2, 89~96, 2016
- Anti-interleukin-33 Reduces Ovalbumin-Induced Nephrotoxicity and Expression of Kidney Injury Molecule-1, INTERNATIONAL NEUROUROLOGY JOURNAL, Vol.20,No.2, 114~121, 2016
- The Alzheimer's Disease Neuroimaging Initiative 2 Biomarker Core: A review of progress and plans, ALZHEIMERS & DEMENTIA, Vol.11,No.7, 772~791, 2015
- Differences in CYP2C9 genotype and enzyme activity between Swedes and Koreans of relevance for personalized medicine: Role of ethnicity, genotype, smoking, age, and sex, OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY, Vol.19,No.6, 346~353, 2015
- Activation of the 5 '-AMP-Activated Protein Kinase in the Cerebral Cortex of Young Senescence-Accelerated P8 Mice and Association with GSK3 beta- and PP2A-Dependent Inhibition of p-tau(396) Expression, JOURNAL OF ALZHEIMERS DISEASE, Vol.46, 249~259, 2015
- A Consensus in Korea Regarding a Protocol to Reduce Preanalytical Sources of Variability in the Measurement of the Cerebrospinal Fluid Biomarkers of Alzheimer's Disease, JOURNAL OF CLINICAL NEUROLOGY, Vol.11, 132~141, 2015
- Role of Cerebrospinal Fluid Biomarkers in Clinical Trials for Alzheimer's Disease Modifying Therapies, KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY, Vol.18,No.6, 447~456, 2014
- What is the Clinical Significance of Cerebrospinal Fluid Biomarkers in Parkinson’s disease? Is the Significance Diagnostic or Prognostic?, Experimental Neurobiology, Vol.23,No.4, 352~364, 2014
- Prediction of Glycated Hemoglobin Levels at 3 Months after Metabolic Surgery Based on the 7-Day Plasma Metabolic Profile, PLOS ONE, Vol.9,No.11, 2014
- Mast cell activation and response to tolterodine in the rat urinary bladder in a chronic model of intravesical protamine sulfate and bacterial endotoxin-induced cystitis, MOLECULAR MEDICINE REPORTS, Vol.10, 670~676, 2014
- Cytometric parameters and the activity of signaling proteins in association with the compensation or decompensation of bladder function in an animal experimental model of partial bladder outlet obstruction, INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, Vol.32,No.6, 1435~1441, 2013
- Association of cerebrospinal fluid b-amyloid 1-42, T-tau, P-tau181, and a-synuclein levels with clinical features of drug-naive patients with early Parkinson disease., JAMA NEUROLOGY, Vol.70, 1277~1287, 2013
- Clinical utility and analytical challenges in measurement of cerebrospinal fluid amyloid-b1-42 and tau proteins as Alzheimer disease biomarkers, CLINICAL CHEMISTRY, Vol.59,No.6, 2013
- Bupivacaine-induced cytotoxicity related to endoplasmic reticulum stress pathways in SH-SY5Y cells, Molecular & Cellular Toxicology, Vol.9,No.2, 141~147, 2013
- Bupivacaine-induced cytotoxicity related to endoplasmic reticulum stress pathways in SH-SY5Y cells, Molecular & Cellular Toxicology, Vol.9,No.2, 141~147, 2013
- Biochemical characterization of a new recombinant TNF receptor-hyFc fusion protein expressed in CHO cells, PROTEIN EXPRESSION AND PURIFICATION, Vol.87,No.1, 17~26, 2013
- Antihypertensive and ACE Inhibitory Effects of Novel Isoflavone-free Black Soy Peptide Mixture, YAKHAK HOEJI, Vol.56,No.5, 309~313, 2012
- Effect of Anti-Siglec-F Antibody and Reactive Oxygen Species Blocking on Histamine Release in Urinary Bladder of Ovalbumin-Treated Mice, International Neurourology Journal, Vol.16,No.3, 122~125, 2012
- Antihypertensive Effects of Novel Isoflavone-Free Black Soy Peptide Mixture as HO-1 Inducer, YAKHAK HOEJI, Vol.56,No.3, 191~197, 2012
- Simultaneous analysis of cerebrospinal fluid biomarkers using microsphere-based xMAP multiplex technology for early detection of Alzheimer's disease, METHODS, Vol.56,No.4, 484~493, 2012
- Bupropion, an atypical antidepressant, induces endoplasmic reticulum stress and caspase-dependent cytotoxicity in SH-SY5Y cells, TOXICOLOGY, Vol.285,1-2, 1~7, 2011
- Genetic polymorphisms in the serotonin receptor type 3B gene (HTR3B) and the clinical response to ondansetron in Koreans, Molecular & Cellular Toxicology, Vol.7,No.2, 148~156, 2011
- Application of liquid chromatography tandem mass spectrometry for the simultaneous quantification of multiple non-opioid drugs in human plasma, Molecular & Cellular Toxicology, Vol.7,No.2, 185~189, 2011
- Increased Expression of Hepatic Organic Cation Transporter 1 and Hepatic Distribution of Metformin in High-fat Diet-induced Obese Mice, DRUG METABOLISM AND PHARMACOKINETICS, Vol.25,No.4, 392~397, 2010
- Mitotic catastrophe induced by overexpression of budding yeast Rad2p, YEAST, Vol.27,No.7, 399~411, 2010
- Metformin-Induced Expression of Urethral nNOS and AMPKalpha Improves Voiding Dysfunctions in Type 2 Goto-Kakizaki Diabetic Rats, NITRIC OXIDE-BIOLOGY AND CHEMISTRY, Vol.22, S91~S91, 2010
- Inhibition of IKK-beta: A new development in the mechanism of the anti-obesity effects of PTP1B inhibitors SA18 and SA32, BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, Vol.20, 1075~1077, 2010
- In vivo and in vitro application of black soybean peptides in the amelioration of endoplasmic reticulum stress and improvement of insulin resistance, LIFE SCIENCES, Vol.86,7-8, 267~274, 2010
- Pharmacokinetic and pharmacodynamic interaction between metformin and (-)-epigallocatechin-3-gallate., Molecular & Cellular Toxicology, Vol.5,No.4, 298~303, 2009
- In vivo and In vitro Studies on the Protective Effects of Silymarin against the Homocysteine-induced Hepatic ER stress, Molecular & Cellular Toxicology, Vol.5, 55~55, 2009
- Induction of endoplasmic reticulum stress and JNK-dependent neuronal cell death by bupropion, Molecular & Cellular Toxicology, Vol.5, 55~55, 2009
- Differential cytotoxicity of drugs acting in the central nervous system in SH-SY5Y cells: toxic mechanisms of fluoxetine and haloperidol, Molecular & Cellular Toxicology, Vol.5, 55~55, 2009
- Function of yeast RAD2 in caspase-independent delayed cell death, Molecular & Cellular Toxicology, 2009
- Deleterious effects of silymarin on the expression of genes controlling endothelial nitric oxide synthase activity in carbon tetrachloride-treated rat livers, LIFE SCIENCES, Vol.85, 281~290, 2009
- Inhibition of 6-hydroxydopamine-induced endoplasmic reticulum stress by L-carnosine in SH-SY5Y cells, NEUROSCIENCE LETTERS, Vol.459,No.1, 7~10, 2009
- Effects of obesity on the hepatic expression of organic cation transporter 1 (SLC22A1), Molecular & Cellular Toxicology, Vol.5,No.3, 66~66, 2009
- Effect of bisphenol A on insulin-mediated glucose metabolism in vivo and in vitro, Molecular & Cellular Toxicology, Vol.4,No.4, 348~354, 2008
- Expression of death receptor 4 induces caspase-independent cell death in MMS-treated yeast, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, Vol.376, 305~309, 2008
- Influence of CYP2D6*10 on the pharmacokinetics of metoprolol in healthy koreans volunteers, JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS, Vol.33, 567~573, 2008
- Role of caveolin-1 in indomethacin-induced death of human hepato-adenocarcinoma SK-Hep1 cells, KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY, Vol.12,No.4, 143~148, 2008
- Novel black soy peptides with antiobesity effects: activation of leptin-like signaling and AMP-activated protein kinase, INTERNATIONAL JOURNAL OF OBESITY, Vol.32, 1161~1170, 2008
- Association between complement factor H gene polymorphisms and neovascular age-related macular degeneration in Koreans, INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, Vol.49,No.5, 2071~2076, 2008
- Polymorphic lengths of dinucleotide (GT)(n) repeats in upstream of human nNOS exon 1f gene play a role in modulating the nNOS transcription: Clinical implications, Molecular & Cellular Toxicology, Vol.4,No.1, 11~15, 2008
- Neuronal nitric oxide-mediated cytotoxicity in trophoblast cells induced by increase of intracellular calcium, Molecular & Cellular Toxicology, Vol.4,No.1, 16~21, 2008
- Enhanced Activity of Flavin-containing Monooxygenase in Human Subjects with High Body Mass Index and in Obese Mice Fed a High-fat Diet, Molecular & Cellular Toxicology, 41, 5~10, 2008
- Effects of CYP1A2*1C and CYP1A2*1F genotypes on the activity and inducibility of CYP1A2 determined by urinary caffeine metabolite ratio in Koreans, Molecular & Cellular Toxicology, Vol.3,No.4, 314~319, 2007
- Cytotoxicity by lead-induced nNOS phosphorylation in a dopaminergic CATH.a cells: Roles of protein kinase A, Molecular & Cellular Toxicology, Vol.3,No.4, 215~221, 2007
- Prevention of olanzapine-induced toxicities of weight gain and inflammatory reactions by coadministration with green tea or its major component phenolic epigallocatechin 3-gallate in mouse, Molecular & Cellular Toxicology, Vol.3,No.2, 127~131, 2007
- Genetic Polymorphisms in the ABCB1 gene and the effects of fentanyl in Koreans, CLINICAL PHARMACOLOGY & THERAPEUTICS, Vol.81,No.4, 539~546, 2007
- The correlation between Genetic Polymorphism of OPRM1(A118G)/MDR1(C3435T) and Analgesia and Adverse Effects by Epidural Morphine, 대한마취과학회지, Vol.52,No.1, 16~22, 2007
- Excessive nitric oxide attenuates leptin-mediated signal transducer and activator of transcription 3 activation, LIFE SCIENCES, Vol.80,No.7, 609~617, 2007
- Effects of genetic polymorphisms of MDR1, FMO3 and CYP1A2 on susceptibility to colorectal cancer in Koreans, CANCER SCIENCE, Vol.97, 774~779, 2006
- Leptin inhibits 1-methyl-4-phenylpyridinium-induced cell death in SH-SY5Y cells, NEUROSCIENCE LETTERS, Vol.407, 240~243, 2006
- Influence of 5-HT3b receptor AAG deletion mutation and CYP2D6*10 on the ondansetron treatment, 대한마취과학회지, 501, 84~89, 2006
- Protective Effects of Vitamin E on Endocrine Disruptors, PCB-induced Dopaminergic Neurotoxicity, TOXICOLOGY, Vol.216, 140~146, 2005
- Enhanced susceptibility to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity in high-fat diet-induced obesity, FREE RADICAL BIOLOGY AND MEDICINE, 386, 806~816, 2005
- Effects of green tea extract administration on the pharmacokinetics of clozapine in rats, JOURNAL OF PHARMACY AND PHARMACOLOGY, 573, 311~316, 2005
- Changes of body weight, blood glucose and lipid levels in patients with schizophrenia after long-term clozapine treatment, The Korean Journal of Psychopharmacology, 162, 130~138, 2005
- Hepatic flavin-containing monooxygenase activity attenuated by cGMP-independent nitric oxide-mediated mRNA destabilization, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, Vol.324, 409~416, 2004
- Flavin-containing monooxygenase activity can be inhibited by nitric oxide-mediated S-nitrosylation, LIFE SCIENCES, Vol.75, 2559~2572, 2004
- Secondary Fish-odor syndrome can be acquired by nitric oxide-mediated impairment of flavin-containing monooxygenase in hepatitis B virus-infected patients, THE KOREAN JOURNAL OF Physiology & Pharmacology, Vol.8, 213~218, 2004
- Inhibition of aroclor 1254-induced depletion of stored calcium prevents the cell death in catecholaminergic cells, TOXICOLOGY, Vol.200, 93~101, 2004
- Alteration of substrate specificity by common variants, E158K/E308G and V257M, in human hepatic drug-metabolizing enzyme, flavin-containing monooxygenase 3, The Korean Journal of Physiology & Pharmacology, Vol.7, 157~162, 2003
- Aroclor 1254-induced cytotoxicity in catecholaminergic CATH.a cells related to the inhibition of nitric oxide production., TOXICOLOGY, Vol.177, 157~166, 2002
- Ethnic differences in allelic frequency of two flavin-containing monooxygenase 3 (FMO3) polymorphism: linkage and effects on in vivo and in vitro FMO activities, PHARMACOGENETICS, Vol.12, 77~80, 2002
- Ethnic differences in human flavin-containing monooxygenase 2 (FMO2) polymorphism: detection of expressed protein in African-Americans., TOXICOLOGY AND APPLIED PHARMACOLOGY, Vol.168, 216~224, 2000
- Differential and constitutive expression of neuronal, inducible and endothelial nitric oxide synthase mRNAs and proteins in pathologically normal human tissues., NITRIC OXIDE-BIOLOGY AND CHEMISTRY, Vol.4, 459~471, 2000
- Effect of age and smoking on in vivo CYP1A2, flavin-containing monooxygenase, and xanthine oxidase activities in Koreans: Determination by caffeine metabolism., CLINICAL PHARMACOLOGY & THERAPEUTICS, Vol.67, 258~266, 2000
- Phenotypes of flavin-containing monooxygenase (FMO) activity determined by ranitidine N-oxidation are positively correlated with genotypes of linked FMO3 gene mutations in a Korean population., PHARMACOGENETICS, Vol.10, 67~78, 2000
- Phenotyping of flavin-containing monooxygenase using caffeine metabolism and genotyping of FMO3 gene in a Korean population, PHARMACOGENETICS, Vol.9, 155~164, 1999
Books펼치기
- 임상약동학의 이해, 신일상사, 2002
Book Chapters
Patents펼치기
- 근감소증의 원인이되는 근육 amyloid beta 생성 효소인 BACE1(beta-secretase) 억제 방법 , 2024
- 줄기세포 유래 베지클을 포함하는 근감소증 질환 예방 또는 치료용 조성물 , 2024
- 3차원 ＤＮＡ 나선형 솔 및 치솔 (3 Dimensional DNA Spiral Brush and Tooth Brush), 2008
- 연골재생제로서 아피제닌을 함유하는 골관절염 치료 조성물, 2004
Citation and Awards펼치기
- 최우수논문상, 대한약리학회, 2016.11.04.
- 우수 논문 발표상, 대한 독성 유전단백체 학회, 2008.11.08.
- 우수 논문 발표상, 대한 독성 유전 단백체 학회, 2007.11.02.
- 우수논문발표상, 대한독성유전단백체학회, 2006.11.07.
- Travel Award, The 3rd International Conference on the Biology, Chemistry and Therapeutic Application of Nitric Oxi, 2004.05.24.